What are liver fibrosis biomarkers
Automated blood test for liver fibrosis
January 31, 2012
Siemens offers the first rapid, automated biomarker test for diagnosing and assessing liver fibrosis. The ELF test (Enhanced Liver Fibrosis Test) takes around an hour. All he needs is a blood sample.
The new test was developed by Siemens Healthcare together with University College London and can be used as a routine test on the Siemens ADVIA Centaur immunoassay systems.
With the automated ADVIA Centaur ELF test, both the severity and the risk of further progression of liver fibrosis can now be detected quickly and gently. He investigates three direct blood serum biomarkers: hyaluronic acid (HA), procollagen III N-terminal propeptide (PIIINP) and the tissue inhibitor of metal proteinase 1 (TIMP-1). These direct biomarkers are molecules that are involved in the development of fibrosis. In the test, special reagents react with the biomarkers and generate light in the process. The more intense this chemiluminescence, the more biomarkers there are.
The results of the three biomarkers are converted into the ELF score using a special algorithm, which indicates the degree of fibrosis. The combination of the three biomarkers increases the accuracy of the test. As an international clinical study showed, the ELF test can precisely differentiate between minor, moderate and severe fibroses.
Press release Siemens, January 26, 2012
Fight hepatitis C together
April 29, 2021: PLUS initiative
April 28, 2021: STI as a predictor of reinfection
COVID-19 and Public Health
April 28, 2021: How did the public health service react to Corona in Germany?
Scholarship German Liver Foundation
April 27, 2021: Application for an exemption scholarship for 2022 Hepatology is now possible.
April 22, 2021: J & J's vector vaccine also effective against variants
HIV funding program
April 20, 2021: You can apply for the Gilead HIV funding program until June 15, 2021.
Health Department Day
March 19, 2021: The motto for the occasion "Crisis Response"
March 14, 2021: EU approval for Janssen's single-use vaccine
February 22, 2021: Non-quantifiable additional benefit for Hepcludex®
February 17, 2021: Viruses survive in the ejaculate of chronically infected patients
February 11, 2021: Need for clarification and action
Addendum DGVS guidelines HCV
December 10, 2020: DGVS guideline recommends immediate start of therapy for chronic HCV infection.
November 22, 2020: Screening for hepatitis B and C is a new part of the health check-up
November 22, 2020: Addendum to the S3 guideline published
November 15, 2020: Fluzone® High Dose Quadrivalent vaccine for people over 65 on the market
Test, advise, treat!
October 20, 2020: Those interested can find out the most important things about hepatitis C in a new educational video
September 28, 2020: EASL guideline on rare genotypes
September 25, 2020: ENSEMBLE vaccine study started
September 21, 2020: New EASL guideline recommends therapy for everyone.
September 21, 2020: HIV infection under PrEP
This website provides information on all aspects of liver disease. The focus is on the viral hepatitis hepatitis A, hepatitis B, hepatitis C, hepatitis D and hepatitis E, fatty liver and liver cancer. The clinical picture, diagnosis and therapy are treated. Much has changed in the treatment of hepatitis B and hepatitis C in particular. Here you will find an overview of the drugs available for hepatitis B and C, study data, specialist information and current prices. The current information from medicine and industry is aimed at those affected and doctors.
- What are the most popular robotics competitions
- What is imagery
- How widespread is LTE in America
- Can hack people with no information
- What did you eat for Christmas?
- What is good digital painting software
- How are greenhouse gases produced by humans
- Who started mixing milk and tea
- Is your SSN in your driver's license?
- What do you think of Michio Kaku
- What is Palm Beach FL known for
- Which SIM cards are compatible with Verizon
- How should siblings be clicked on weddings
- What does nautical twilight mean?
- Which parent book helped you a lot
- Less planning means more productivity
- Community college is cheap
- Which voltage detector
- Is there a website for medical records
- Can a Muslim become a US diplomat
- What is Longrich
- What are negative and positive profit margins
- Which Chinese dynasty had the best military?